The Chemistry and Biology of Nitroxyl (HNO) by Fabio Doctorovich,Patrick J. Farmer,Marcelo A. Marti

The Chemistry and Biology of Nitroxyl (HNO) presents first-of-its-kind insurance of the interesting biologically energetic molecule referred to as nitroxyl, or azanone in line with IUPAC nomenclature, which has been often elusive because of its intrinsically excessive reactivity.

This resource presents the medical foundation to appreciate the chemistry, biology, and technical facets had to care for HNO. construction on twenty years of nitric oxide and nitroxyl learn, the editors and authors have created an necessary consultant for investigators throughout a wide selection of components of chemistry (inorganic, natural, organometallic, biochemistry, actual, and analytical); biology (molecular, mobile, physiological, and enzymology); pharmacy; and medicine.

This e-book starts via exploring the original molecule’s constitution and reactivity, together with very important reactions with small molecules, thiols, porphyrins, and key proteins, earlier than discussing chemical and organic assets of nitroxyl. complex chapters talk about tools for either trapping and detecting nitroxyl via spectroscopy, electrochemistry, and fluorescent inorganic mobile probing.

Expanding at the compound’s foundational chemistry, this booklet then explores its molecular body structure to supply perception into its organic implications, pharmacological results, and sensible issues.

• Presents the 1st publication on HNO (nitroxyl or azanone), an more and more very important molecule in biochemistry and pharmaceutical research
• Provides a necessary insurance of HNO’s chemical constitution and important reactions, together with functional information on operating with this hugely reactive molecule
• Contains top of the range content material from well-known specialists in either and academia